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Animal Models
C57BL/6JCya-Fbxw2em1/Cya
Fbxw2 is located on chromosome 2 of mice. Nuclease Technology was used to design sgRNA; Fbxw2 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Fbxw18em1/Cya
Fbxw18 is located on chromosome 9 of mice. Nuclease Technology will be used to design sgRNA; Fbxw18 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Fbxw21em1/Cya
Fbxw21 is located on chromosome 9 of mice. Nuclease Technology was used to design sgRNA; Fbxw21 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Fbxw20em1/Cya
Fbxw20 is located on chromosome 9 of mice. Nuclease Technology was used to design sgRNA; Fbxw20 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Fbxw10em1/Cya
Fbxw10 is located on chromosome 11 of mice. Nuclease Technology was used to design sgRNA; Fbxw10 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Fbxw11em1/Cya
Fbxw11 is located on chromosome 11 of mice. Nuclease Technology will be used to design sgRNA; Fbxw11 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Fbxw5em1/Cya
Fbxw5 is located on chromosome 2 of mice. Nuclease Technology will be used to design sgRNA; Fbxw5 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Fbxw2em1/Cya
Fbxw2 is located on chromosome 2 of mice. Nuclease Technology will be used to design sgRNA; Fbxw2 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Fbxw10em1/Cya
Fbxw10 is located on chromosome 11 of mice. Nuclease Technology will be used to design sgRNA; Fbxw10 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Fbxw17em1/Cya
Fbxw17 is located on chromosome 13 of mice. Nuclease Technology will be used to design sgRNA; Fbxw17 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
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Global Antibody Drug Industry Development BlueBook (Frost & Sullivan)
Key Insights
The industry is undergoing a rapid transformation driven by next-generation modalities, globalized markets, and upstream technological innovations.
  • Market Structural Shift: Monoclonal antibodies drive steady growth, but ADCs and bispecifics are rapidly accelerating, reshaping the market with higher-value innovations.
  • Chinese Market Globalization: China is actively expanding globally, evidenced by a surge in high-value cross-border license-out deals.
  • Technology-Driven Efficiency: Advanced discovery engines—exemplified by Cyagen's HUGO-Ab platform and AI algorithms—are streamlining candidate screening, optimizing molecular design, and localizing the upstream supply chain.
  • Oncology-Focused Innovation: R&D pipelines remain heavily concentrated on high-incidence malignancies like non-small cell lung cancer, utilizing complex modalities to combat clinical resistance.
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