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Animal Models
C57BL/6JCya-Cygbem1/Cya
Cygb is located on chromosome 11 of mice. Nuclease Technology was used to design sgRNA; Cygb knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Gyg1em1/Cya
Gyg1 is located on chromosome 3 of mice. Nuclease Technology was used to design sgRNA; Gyg1 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Pygbem1/Cya
Pygb is located on chromosome 2 of mice. Nuclease Technology was used to design sgRNA; Pygb knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Pyglem1/Cya
Pygl is located on chromosome 12 of mice. Nuclease Technology was used to design sgRNA; Pygl knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Pygmem1/Cya
Pygm is located on chromosome 19 of mice. Nuclease Technology will be used to design sgRNA; Pygm knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Pygmem1/Cya
Pygm is located on chromosome 19 of mice. Nuclease Technology was used to design sgRNA; Pygm knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Pygbem1/Cya
Pygb is located on chromosome 2 of mice. Nuclease Technology was used to design sgRNA; Pygb knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Lyg1em1/Cya
Lyg1 is located on chromosome 1 of mice. Nuclease Technology will be used to design sgRNA; Lyg1 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Myg1em1/Cya
Myg1 is located on chromosome 15 of mice. Nuclease Technology will be used to design sgRNA; Myg1 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Lyg2em1/Cya
Lyg2 is located on chromosome 1 of mice. Nuclease Technology will be used to design sgRNA; Lyg2 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
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Global Antibody Drug Industry Development BlueBook (Frost & Sullivan)
Key Insights
The industry is undergoing a rapid transformation driven by next-generation modalities, globalized markets, and upstream technological innovations.
  • Market Structural Shift: Monoclonal antibodies drive steady growth, but ADCs and bispecifics are rapidly accelerating, reshaping the market with higher-value innovations.
  • Chinese Market Globalization: China is actively expanding globally, evidenced by a surge in high-value cross-border license-out deals.
  • Technology-Driven Efficiency: Advanced discovery engines—exemplified by Cyagen's HUGO-Ab platform and AI algorithms—are streamlining candidate screening, optimizing molecular design, and localizing the upstream supply chain.
  • Oncology-Focused Innovation: R&D pipelines remain heavily concentrated on high-incidence malignancies like non-small cell lung cancer, utilizing complex modalities to combat clinical resistance.
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