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Animal Models
C57BL/6JCya-Ctswem1/Cya
Ctsw is located on chromosome 19 of mice. Nuclease Technology was used to design sgRNA; Ctsw knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Ube2wem1/Cya
Ube2w is located on chromosome 1 of mice. Nuclease Technology was used to design sgRNA; Ube2w knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Cenpwem1/Cya
Cenpw is located on chromosome 10 of mice. Nuclease Technology will be used to design sgRNA; Cenpw knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Opn1swem1/Cya
Opn1sw is located on chromosome 6 of mice. Nuclease Technology was used to design sgRNA; Opn1sw knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Npwem1/Cya
Npw is located on chromosome 17 of mice. Nuclease Technology will be used to design sgRNA; Npw knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Selenowem1/Cya
Selenow is located on chromosome 7 of mice. Nuclease Technology will be used to design sgRNA; Selenow knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Pigwem1/Cya
Pigw is located on chromosome 11 of mice. Nuclease Technology will be used to design sgRNA; Pigw knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Gpkowem1/Cya
Gpkow is located on chromosome X of mice. Nuclease Technology will be used to design sgRNA; Gpkow knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Ube2wem1/Cya
Ube2w is located on chromosome 1 of mice. Nuclease Technology will be used to design sgRNA; Ube2w knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Opn1mwem1/Cya
Opn1mw is located on chromosome X of mice. Nuclease Technology will be used to design sgRNA; Opn1mw knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
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Global Antibody Drug Industry Development BlueBook (Frost & Sullivan)
Key Insights
The industry is undergoing a rapid transformation driven by next-generation modalities, globalized markets, and upstream technological innovations.
  • Market Structural Shift: Monoclonal antibodies drive steady growth, but ADCs and bispecifics are rapidly accelerating, reshaping the market with higher-value innovations.
  • Chinese Market Globalization: China is actively expanding globally, evidenced by a surge in high-value cross-border license-out deals.
  • Technology-Driven Efficiency: Advanced discovery engines—exemplified by Cyagen's HUGO-Ab platform and AI algorithms—are streamlining candidate screening, optimizing molecular design, and localizing the upstream supply chain.
  • Oncology-Focused Innovation: R&D pipelines remain heavily concentrated on high-incidence malignancies like non-small cell lung cancer, utilizing complex modalities to combat clinical resistance.
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