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NKG-hIL6
Product ID:
I001176
Background:
NKG
Documents:
Click here to download >
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Basic Information
Model Name
NKG-hIL6
Product ID
I001176
Gene Name
Il2rg, IL6
Background
NKG
Gene Alias
gc; p64; [g]c; CD132; gamma(c); CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2
Classification
Immunodeficient Mouse Models
NCBI ID
16186, 3569
Phenotype
MGI:96551, MGI:96559
Chromosome
X
More
Rare Disease Data Center >>
Document
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Note
Note: When using this mouse strain in a publication, please cite “NKG-hIL6 mice (Catalog I001176) were purchased from Cyagen.”
Strain Description
NKG-hIL6 mice were constructed by introducing the human IL6 gene into the genome of NKG mice. Compared to NKG mice, NKG-hIL6 mice can efficiently and rapidly rebuild human CD45+ leukocytes during HSC reconstruction. These mice are valuable for developing tumor immunotherapies and drug evaluations.
Application Area
Area
Construction of an immune system humanized mouse model
Area
Research on the human immune system and hematopoietic systems
Area
Human-derived cell line xenograft (CDX) and patient-derived xenograft (PDX)
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