NKG-hIL6
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
NKG-hIL6
Product ID
I001176
Background
NKG
Gene Alias
gc; p64; [g]c; CD132; gamma(c); CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2
Classification
Immunodeficient Mouse Models
Chromosome
X
Document
Note: When using this mouse strain in a publication, please cite “NKG-hIL6 mice (Catalog I001176) were purchased from Cyagen.”
Strain Description
NKG-hIL6 mice were constructed by introducing the human IL6 gene into the genome of NKG mice. Compared to NKG mice, NKG-hIL6 mice can efficiently and rapidly rebuild human CD45+ leukocytes during HSC reconstruction. These mice are valuable for developing tumor immunotherapies and drug evaluations.
Application Area
Construction of an immune system humanized mouse model
Research on the human immune system and hematopoietic systems
Human-derived cell line xenograft (CDX) and patient-derived xenograft (PDX)
Validation Data