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Catalog Number: I001172
Strain Name: C57BL/6JCya-Cd68em1(P2A-iCre)/Cya
Genetic Background: C57BL/6JCya
Examples of Expressing Tissues/Cells: monocytes and macrophages
Strain Description
The TGA stop codon was replaced with the "P2A-iCre-WPRE-BGH pA" cassette. Cre recombinase is expressed under the regulatory control of Cd68 gene elements, without impacting the endogenous expression of the Cd68 gene.
Announcement
The insertion site of the Cre recombinase gene expression cassette in this strain is located on chromosome 11. Please avoid breeding with gene-edited mice targeting genes on the same chromosome as the Cre mouse when conducting mating.