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Catalog Number: I001160
Strain Name: C57BL/6JCya-Csf1rem1(IRES-iCre)/Cya
Genetic Background: C57BL/6JCya
Examples of Expressing Tissues/Cells: macrophages, dendritic cells, and granulocytes derived from bone marrow
Strain Description
The "IRES-iCre" cassette was inserted downstream of the TGA stop codon. Cre recombinase is expressed under the regulatory control of Csf1r gene elements, without impacting the endogenous expression of the Csf1r gene.
Announcement
The insertion site of the Cre recombinase gene expression cassette in this strain is located on chromosome 18. Please avoid breeding with gene-edited mice targeting genes on the same chromosome as the Cre mouse when conducting mating.