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Catalog Number: I001173
Strain Name: C57BL/6JCya-Klrd1em1(P2A-iCre)/Cya
Genetic Background: C57BL/6JCya
Examples of Expressing Tissues/Cells: bone marrow and natural killer cells (NK cells)
Strain Description
The TAA stop codon was replaced with the "P2A-iCre-WPRE-BGH pA" cassette. Cre recombinase is expressed under the regulatory control of Klrd1 gene elements, without impacting the endogenous expression of the Klrd1 gene.
Announcement
The insertion site of the Cre recombinase gene expression cassette in this strain is located on chromosome 6. Please avoid breeding with gene-edited mice targeting genes on the same chromosome as the Cre mouse when conducting mating.