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B6-RCL-hLPA/Alb-cre/TG (APOB)
Product ID:
C001553
Background:
C57BL/6Cya
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Strain Description
The B6-RCL-hLPA/Alb-cre/TG (APOB) mice express human LP(a) and ApoB, two risk factors for cardiovascular disease. It can be used in the study of hyperlipidemia, stroke, coronary heart disease, familial hypercholesterolemia (FH), and other atherosclerotic cardiovascular diseases (ASCVD). Internal data (not shown) indicates that, compared to the Cyagen strain B6-LPA (CKI) /Alb-Cre & Tg (APOB) mice (Catalog No. C001494), this model exhibits a more stable expression of human LPA protein at different ages. Please choose the model based on the experimental need for continuous stability of human LPA protein expression.
Application Area
Area
Development and evaluation of LP(a) and ApoB targeted drugs
Area
Research on familial hypercholesterolemia (FH)
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Research on atherosclerotic cardiovascular disease (ASCVD)
Area
Research on other cardiovascular diseases (CVD)
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