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TurboKnockoutᵀᴹ Reliability
TurboKnockoutᵀᴹ -based, off-target-free, IP-safe, and large-fragment-ready.
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Product

当前,基因编辑小鼠已成为生命科学研究中不可或缺的工具。但在实际科研场景下,从研读海量文献到确认项目方向,从构建模型到饲养繁育,你与最终研究成果之间总隔着漫长的等待。如何及时跟进前沿热点,快速到手所需的小鼠模型,进而抢跑科研赛道?

赛业生物可提供两种KO/CKO现货选择,快至48小时发货,让实验不必等待:

选择一:畅销品系纯合子现货,稳定供应,快速发货——这里汇集了常年位于订购榜单前列的明星模型,如免疫、神经、代谢、肿瘤等领域的经典品系。它们经过了多篇高分文献的使用与验证,模型稳定、表型明确。

选择二:实时活体小鼠秒杀频道,限时上新,先到先得——我们在这里开放一个实时更新、库存动态变化的KO/CKO活体模型抢购专区,库存不定期放出,售完即止,并会不断补充新的小鼠品系。

此外,赛业生物还可以提供Cre工具鼠、诱导型Cre工具鼠、荧光标记模型等数百种现货模型,灵活匹配各类基因编辑策略。 欢迎拨打 400-680-8038或邮件至 info@cyagen.com或点击侧边栏 在线咨询联系我们。

Cre-loxP重组酶系统使用手册
Cre-loxP重组酶系统使用手册
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畅销品系纯合子现货秒杀
实时活体小鼠秒杀
产品名称 NCBI ID 项目类型 品系 表型提示 应用领域 订购
{{_.name}} {{_.gene_id}} {{_.modify}} {{_.strain}} {{_.phenotype}} {{_.apply}}
尊敬的老师,非常抱歉,您查询的 {{table.keyword}} 品系不在本期秒杀品系内。您可以通过 许愿池 留言,我们助你加速上线/返场!
产品名称 NCBI ID 项目类型 品系 表型提示 应用领域 订购
{{_.name}} {{_.gene_id}} {{_.modify}} {{_.strain}} {{_.phenotype}} {{_.apply}}
尊敬的老师,非常抱歉,您查询的 {{table2.keyword}} 品系不在本期秒杀品系内。您可以通过 许愿池 留言,我们助你加速上线/返场!
已发表高分文献精选

1. RIPK1 senses S-adenosylmethionine scarcity to drive cell death and inflammation.
Cell metabolism(2025)IF=30.9 引用产品:Prmt5条件性敲除小鼠

2. Targeting GSDME-mediated macrophage polarization for enhanced antitumor immunity in hepatocellular carcinoma.
Cellular & molecular immunology(2024)IF=19.8 引用产品:Gsdme敲除小鼠

3. Neutrophil-macrophage communication via extracellularvesicle transfer promotes itaconate accumulation andameliorates cytokine storm syndrome.
Cellular & molecular immunology(2024)IF=19.8 引用产品:Acod1敲除小鼠

产品优势

交付周期短

精选活体基因敲除小鼠、条件性敲除小鼠,快至48小时内交付,帮助研究人员以超低时间成本获得现货小鼠以投入实验, 最大程度地加快科研进度。

小鼠模型构建平台成熟稳定

国际知名专家团队领衔,近20年来已支持多项重大科研项目顺利实施,拥有上万例小鼠模型构建经验,平台技术成熟稳定。

覆盖多个热门研究领域

赛业生物自研的疾病模型鼠可应用于免疫、肿瘤、罕见病、心血管、神经、眼科等20+个研究方向,智能化满足客户在基础研究和新药研发的项目需求。每周精选品系上新,跟进行业前沿热点!

ISO9001:2015/OLAW认证及AAALAC认可多重质控

ISO9001:2015和OLAW认证确保向广大专家学者提供的所有产品和技术服务符合国际标准,AAALAC认可表明了赛业生物尊重动物福利和伦理、重视生物安全的负责任态度。

国际一流的硬件设施

SPF级的饲养环境,为您的实验数据提供更可靠的依据。中心配备有医用级的地轨灭菌器、全自动笼盒连续清洗机、臭氧紫外消毒传递设施与全自动的废弃物收集和除味系统,以保障动物房的高效运行。
Overview
FAQs
Frequently Asked Questions (FAQs)
How many copies of the transgene are typically integrated?
Regular transgenesis often results in multiple tandem copies at a single integration site. This may lead to higher expression, but also carries risks of silencing or variable expression.
Is the integration site controlled or random?
Integration is random, which may lead to position effects or disruption of endogenous genes. Screening multiple founder lines is essential.
How long does the process take?
You can expect to receive founder animals in 2–5 months, depending on project complexity and strain availability.
Can regular transgenesis be used for precise gene knockin or conditional knockout?
No. For site-specific modifications, consider advanced technologies such as [Targeted Gene Editing] or [TurboKnockout®].
Citation Database
Molecular Therapy: Methods & Clinical Development, March, 2025
Intracranial AAV administration dose-dependently recruits B cells to inhibit the AAV redosing
【Other】
Gut, February, 2025
E-twenty-six-specific sequence variant 5 (ETV5) facilitates hepatocellular carcinoma progression and metastasis through enhancing polymorphonuclear myeloid-derived suppressor cell (PMN-MDSC)-mediated immunosuppression
【Other】
Cell Death & Disease, February, 2025
Mcm5 mutation leads to silencing of Stat1-bcl2 which accelerating apoptosis of immature T lymphocytes with DNA damage
【Other】
Molecular Therapy, February, 2025
Single-cell data-driven design of armed oncolytic virus to boost cooperative innate-adaptive immunity against cancer
【Other】
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Global Antibody Drug Industry Development BlueBook (Frost & Sullivan)
Key Insights
The industry is undergoing a rapid transformation driven by next-generation modalities, globalized markets, and upstream technological innovations.
  • Market Structural Shift: Monoclonal antibodies drive steady growth, but ADCs and bispecifics are rapidly accelerating, reshaping the market with higher-value innovations.
  • Chinese Market Globalization: China is actively expanding globally, evidenced by a surge in high-value cross-border license-out deals.
  • Technology-Driven Efficiency: Advanced discovery engines—exemplified by Cyagen's HUGO-Ab platform and AI algorithms—are streamlining candidate screening, optimizing molecular design, and localizing the upstream supply chain.
  • Oncology-Focused Innovation: R&D pipelines remain heavily concentrated on high-incidence malignancies like non-small cell lung cancer, utilizing complex modalities to combat clinical resistance.
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