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Atp7b KO
Product ID:
C001267
Background:
C57BL/6NCya
Documents:
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Strain Description
This strain is an Atp7b deletion mouse model, which uses gene editing technology to knock out Atp7b, the homolog of the human ATP7B gene in mice that lack the expression of ATP7B protein and can be used in the study of disorders related to copper metabolisms such as Wilson's disease, acute liver failure, and steatohepatitis. The heterozygous Atp7b KO mice are viable and fertile, and homozygous mice have a reduced life expectancy.
Application Area
Area
Copper Metabolism Research
Area
Wilson’s Disease Research
Area
Acute Liver Failure Research
Area
Steatohepatitis Research
Area
Other Research Related to Copper Metabolism Disorders
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