Cx3cr1-iCre
Product ID:
C001391
Background:
C57BL/6JCya
Documents:
Expressing Tissues/Cells:
Microglia in the brain, etc.
Product Type
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Genotype
Sex
Quantity
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Basic Information
Model Name
Cx3cr1-iCre
Product ID
C001391
Gene Name
Background
C57BL/6JCya
Gene Alias
mCX3CR1
Classification
Cre Driver Lines
NCBI ID
Phenotype
Chromosome
9
Document
Note: When using this mouse strain in a publication, please cite “Cx3cr1-iCre mice (Catalog C001391) were purchased from Cyagen.”
Strain Description
Cx3cr1-iCre mice are generated using gene editing technology to replace the coding sequence (CDS) region of the endogenous mouse Cx3cr1 gene with an improved Cre recombinase (iCre) expression element. This results in an expression pattern of Cre recombinase that is similar to that of the endogenous gene. When these mice are crossed with mice containing a loxP site-flanked sequence, Cre recombinase-mediated recombination leads to deletion of the flanked sequence in brain microglia and macrophages in other parts of the offspring mice.
Validation Data