Nr2e3 KO
Product Type
Age
Genotype
Sex
Quantity
Price:
Contact for Pricing
Strain Description
This strain is a mouse Nr2e3 knockout model that uses gene editing technology to knock out the homolog of the human NR2E3 gene in mice. The absence of the Nr2e3 gene in mice can lead to the appearance of pathological retinal spots, late-onset retinal degeneration, reduced ERG amplitude in rod cells, and folding and vortices in the photoreceptor layer. The Nr2e3 KO mice can be used as a model for enhanced S-cone syndrome (ESCS) research.
Application Area
Enhanced S-Cone Syndrome (ESCS) Research
Retinitis Pigmentosa (RP) Research
Other Retinal Diseases Research
Detailed Information