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B6-hSTING1
Product ID:
C001712
Background:
C57BL/6NCya
Documents:
Click here to download >
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Price:
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Basic Information
Model Name
B6-hSTING1
Product ID
C001712
Gene Name
STING1
Background
C57BL/6NCya
Gene Alias
ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; TMEM173; STING-beta
Classification
Tumor Target Humanized Models,Immune Target Humanized Models,Full-Gene Humanized Models,Neurological Disease Models,Autoimmune Disease Models
NCBI ID
340061
Phenotype
MGI:1919762
Chromosome
5
More
Rare Disease Data Center >>
Document
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Note
Note: When using this mouse strain in a publication, please cite “B6-hSTING1 mice (Catalog C001712) were purchased from Cyagen.”
Strain Description
The B6-hSTING1 mouse is a humanized model constructed by replacing the sequence of the mouse Sting1 gene in situ with the corresponding sequence from the human STING1 gene. The B6-hSTING1 mice can be used to study the pathogenesis of immune-mediated diseases and cancers, as well as for STING1-targeted drug development.
Application Area
Area
STING1-targeted drug screening, development, and evaluation
Area
Research on autoimmune disease
Area
Research on anti-tumor drugs
Validation Data
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