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B6-hGCGR
Product ID:
C001723
Background:
C57BL/6NCya
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Strain Description
The B6-hGCGR mouse is a humanized model constructed by replacing the sequence of the mouse Gcgr gene in situ with the corresponding sequence from the human GCGR gene. The B6-hGCGR mice can be used for studies on obesity, type 2 diabetes, metabolic dysfunction-associated steatohepatitis, and other glucose-related metabolic disorders, as well as for GCGR-targeted drug development.
Application Area
Area
GCGR-targeted drug screening, development, and evaluation
Area
Research on the pathological mechanisms and therapeutic approaches of obesity, type 2 diabetes, and Metabolic Dysfunction - Associated Steatohepatitis (MASH)
Area
Research on other glucose-related metabolic disorders
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