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B6-hANGPTL7
Product ID:
C001789
Background:
C57BL/6JCya
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Strain Description
The B6-hANGPTL7 mouse is a humanized model, constructed by replacing the sequences from 5'UTR to 3'UTR of the endogenous mouse Angptl7 gene with the corresponding human ANGPTL7 gene sequence. B6-hANGPTL7 mice can be used for research into the pathogenesis of glaucoma, type 2 diabetes mellitus (T2DM), and obstructive sleep apnea (OSA). They are also useful for the screening, development, and safety evaluation of ANGPTL7-targeted drugs.
Application Area
Area
ANGPTL7-targeted drug screening, development, and evaluation
Area
Research on the pathological mechanisms and therapeutic approaches of glaucoma
Area
Research on the pathological mechanisms and therapeutic approaches of type 2 diabetes mellitus (T2DM) and obstructive sleep apnea (OSA)
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