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B6-hNRL
Product ID:
C001799
Background:
C57BL/6JCya
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Strain Description
The B6-hNRL mouse is a humanized model, constructed by replacing the sequences from 5'UTR to 3'UTR of the endogenous mouse Nrl gene with the corresponding human NRL gene sequence. B6-hNRL mice can be used for research into the pathogenesis of various inherited retinal degenerative diseases such as Retinitis Pigmentosa (RP). They are also useful for the screening, development, and safety evaluation of NRL-targeted drugs.
Application Area
Area
NRL-targeted drug screening, development, and evaluation
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Research on the pathological mechanisms and therapeutic approaches of various inherited retinal degenerative diseases such as Retinitis Pigmentosa (RP)
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