B6-hTTN
Product Type
Age
Genotype
Sex
Quantity
Price:
Contact for Pricing
Strain Description
The B6-hTTN mouse is a humanized model, constructed by replacing the coding sequences of the endogenous mouse Ttn gene with the coding sequences of the human TTN gene. B6-hTTN mice can be used for research into the pathogenesis of genetic muscle diseases such as familial dilated cardiomyopathy (DCM), early-onset myopathy, and muscular dystrophy. They are also useful for the screening, development, and safety evaluation of TTN-targeted drugs.
Application Area
TTN-targeted drug screening, development, and evaluation
Research on the pathological mechanisms and therapeutic approaches of genetic muscle diseases such as familial dilated cardiomyopathy (DCM), early-onset myopathy, and muscular dystrophy
Detailed Information