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B6-hRAMP1
Product ID:
C001822
Background:
C57BL/6JCya
Documents:
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Strain Description
The B6-hRAMP1 mouse is a humanized model, constructed by replacing the partial coding sequences of mouse Ramp1 exon 1 with the Kozak-human RAMP1 CDS-3'UTR of mouse Ramp1-WPRE-BGH pA cassette. B6-hRAMP1 mice can be used for research into the pathogenesis of migraine, essential hypertension, cerebral infarction, acute lung injury, chronic inflammation, certain cancers, and metabolic disorders. They are also useful for the screening, development, and safety evaluation of RAMP1-targeted drugs.
Application Area
Area
RAMP1-targeted drug screening, development, and evaluation
Area
Research on the pathological mechanisms and therapeutic approaches of migraine, essential hypertension, cerebral infarction, acute lung injury, and chronic inflammation
Area
Research on the pathological mechanisms and therapeutic approaches of certain cancers such as prostate cancer and gastric cancer
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