Tagln-MerCreMer
Product ID:
C001830
Background:
C57BL/6JCya
Documents:
Expressing Tissues/Cells:
Smooth muscle
Product Type
Age
Genotype
Sex
Quantity
Price:
Contact for Pricing
Basic Information
Model Name
Tagln-MerCreMer
Product ID
C001830
Gene Name
Background
C57BL/6JCya
Gene Alias
Sm22; Sm22a; Ws310
Classification
Cre Driver Lines
NCBI ID
Phenotype
Chromosome
--
Document
Note: When using this mouse strain in a publication, please cite “Tagln-MerCreMer mice (Catalog C001830) were purchased from Cyagen.”
Strain Description
Tagln-MerCreMer mouse is generated by replacing part of the coding sequence in exon 2 of the murine Tagln gene with a tamoxifen-inducible MerCreMer recombinase cassette. Before tamoxifen induction, MerCreMer recombinase is confined to the cytoplasm; only after tamoxifen treatment can MerCreMer translocate into the nucleus to exert its genetic recombination function. When Tagln-MerCreMer mice are crossed with mice containing loxP sites, tamoxifen induction triggers Cre-mediated sequence recombination between loxP sites specifically in the smooth muscle of offspring.
Validation Data