B6-APOE4/htau
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
B6-APOE4/htau
Product ID
C001875
Background
C57BL/6Cya
Gene Alias
AD2; LPG; APO-E; ApoE4; LDLCQ5; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; tau-40; FTDP-17; PPP1R103; Tau-PHF6
Classification
Full-Gene Humanized Models,Neurological Disease Models,Rare Disease Models
Chromosome
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Datasheet
Note: When using this mouse strain in a publication, please cite “B6-APOE4/htau mice (Catalog C001875) were purchased from Cyagen.”
Strain Description
The B6-APOE4/htau mouse is a model generated by crossing B6-APOE4 mice (Catalog No.: C001079) with B6-htau mice (Catalog No.: C001410). It can be used to study the pathogenic mechanisms and therapeutic approaches of neurodegenerative diseases such as Alzheimer’s disease (AD), frontotemporal dementia (FTD), and cerebral amyloid angiopathy (CAA), as well as cardiovascular diseases such as atherosclerosis.
Application Area
Research on neurodegenerative diseases such as Alzheimer’s disease (AD), frontotemporal dementia (FTD), and cerebral amyloid angiopathy (CAA)
Research on cardiovascular diseases such as atherosclerosis
Validation Data