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Animal Models
C57BL/6JCya-Irs2em1/Cya
Irs2 is located on chromosome 8 of mice. Nuclease Technology was used to design sgRNA; Irs2 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Irs1em1/Cya
Irs1 is located on chromosome 1 of mice. Nuclease Technology was used to design sgRNA; Irs1 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Mrs2em1/Cya
Mrs2 is located on chromosome 13 of mice. Nuclease Technology will be used to design sgRNA; Mrs2 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Arsbem1/Cya
Arsb is located on chromosome 13 of mice. Nuclease Technology will be used to design sgRNA; Arsb knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6NCya-Arsaem1/Cya
Arsa is located on chromosome 15 of mice. Nuclease Technology was used to design sgRNA; Arsa knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Frs2em1/Cya
Frs2 is located on chromosome 10 of mice. Nuclease Technology will be used to design sgRNA; Frs2 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Brs3em1/Cya
Brs3 is located on chromosome X of mice. Nuclease Technology will be used to design sgRNA; Brs3 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Arskem1/Cya
Arsk is located on chromosome 13 of mice. Nuclease Technology will be used to design sgRNA; Arsk knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Arsgem1/Cya
Arsg is located on chromosome 11 of mice. Nuclease Technology will be used to design sgRNA; Arsg knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Arsiem1/Cya
Arsi is located on chromosome 18 of mice. Nuclease Technology will be used to design sgRNA; Arsi knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
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Global Antibody Drug Industry Development BlueBook (Frost & Sullivan)
Key Insights
The industry is undergoing a rapid transformation driven by next-generation modalities, globalized markets, and upstream technological innovations.
  • Market Structural Shift: Monoclonal antibodies drive steady growth, but ADCs and bispecifics are rapidly accelerating, reshaping the market with higher-value innovations.
  • Chinese Market Globalization: China is actively expanding globally, evidenced by a surge in high-value cross-border license-out deals.
  • Technology-Driven Efficiency: Advanced discovery engines—exemplified by Cyagen's HUGO-Ab platform and AI algorithms—are streamlining candidate screening, optimizing molecular design, and localizing the upstream supply chain.
  • Oncology-Focused Innovation: R&D pipelines remain heavily concentrated on high-incidence malignancies like non-small cell lung cancer, utilizing complex modalities to combat clinical resistance.
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