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Animal Models
C57BL/6NCya-Eedem1flox/Cya
Eed is located on chromosome 7 of mice. SgRNA and ssDNA were designed using Nuclease Technology; Eed conditional knockout mice were obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Eef2em1/Cya
Eef2 is located on chromosome 10 of mice. Nuclease Technology will be used to design sgRNA; Eef2 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Eea1em1/Cya
Eea1 is located on chromosome 10 of mice. Nuclease Technology was used to design sgRNA; Eea1 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Eef2em1flox/Cya
Eef2 is located on chromosome 10 of mice. SgRNA and ssDNA were designed using Nuclease Technology; Eef2 conditional knockout mice were obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Eedem1/Cya
Eed is located on chromosome 7 of mice. Nuclease Technology will be used to design sgRNA; Eed knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Wee1em1/Cya
Wee1 is located on chromosome 7 of mice. Nuclease Technology will be used to design sgRNA; Wee1 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Mceeem1/Cya
Mcee is located on chromosome 7 of mice. Nuclease Technology will be used to design sgRNA; Mcee knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Wee2em1/Cya
Wee2 is located on chromosome 6 of mice. Nuclease Technology will be used to design sgRNA; Wee2 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Wee1em1flox/Cya
Wee1 is located on chromosome 7 of mice. SgRNA and ssDNA will be designed using Nuclease Technology; Wee1 conditional knockout mice will be obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm will be collected for cryopreservation.
C57BL/6JCya-Mceeem1flox/Cya
Mcee is located on chromosome 7 of mice. SgRNA and ssDNA will be designed using Nuclease Technology; Mcee conditional knockout mice will be obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm will be collected for cryopreservation.
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Global Antibody Drug Industry Development BlueBook (Frost & Sullivan)
Key Insights
The industry is undergoing a rapid transformation driven by next-generation modalities, globalized markets, and upstream technological innovations.
  • Market Structural Shift: Monoclonal antibodies drive steady growth, but ADCs and bispecifics are rapidly accelerating, reshaping the market with higher-value innovations.
  • Chinese Market Globalization: China is actively expanding globally, evidenced by a surge in high-value cross-border license-out deals.
  • Technology-Driven Efficiency: Advanced discovery engines—exemplified by Cyagen's HUGO-Ab platform and AI algorithms—are streamlining candidate screening, optimizing molecular design, and localizing the upstream supply chain.
  • Oncology-Focused Innovation: R&D pipelines remain heavily concentrated on high-incidence malignancies like non-small cell lung cancer, utilizing complex modalities to combat clinical resistance.
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