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Animal Models
C57BL/6JCya-Gsrem1/Cya
Gsr is located on chromosome 8 of mice. Nuclease Technology will be used to design sgRNA; Gsr knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Hgsem1/Cya
Hgs is located on chromosome 11 of mice. Nuclease Technology was used to design sgRNA; Hgs knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Sgshem1/Cya
Sgsh is located on chromosome 11 of mice. Nuclease Technology will be used to design sgRNA; Sgsh knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Rgs6em1/Cya
Rgs6 is located on chromosome 12 of mice. Nuclease Technology will be used to design sgRNA; Rgs6 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Rgs1em1/Cya
Rgs1 is located on chromosome 1 of mice. Nuclease Technology was used to design sgRNA; Rgs1 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Tgs1em1/Cya
Tgs1 is located on chromosome 4 of mice. Nuclease Technology will be used to design sgRNA; Tgs1 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Pgs1em1/Cya
Pgs1 is located on chromosome 11 of mice. Nuclease Technology will be used to design sgRNA; Pgs1 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Rgs2em1/Cya
Rgs2 is located on chromosome 1 of mice. Nuclease Technology will be used to design sgRNA; Rgs2 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Gsnem1/Cya
Gsn is located on chromosome 2 of mice. Nuclease Technology will be used to design sgRNA; Gsn knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Rgs2em1/Cya
Rgs2 is located on chromosome 1 of mice. Nuclease Technology will be used to design sgRNA; Rgs2 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
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Global Antibody Drug Industry Development BlueBook (Frost & Sullivan)
Key Insights
The industry is undergoing a rapid transformation driven by next-generation modalities, globalized markets, and upstream technological innovations.
  • Market Structural Shift: Monoclonal antibodies drive steady growth, but ADCs and bispecifics are rapidly accelerating, reshaping the market with higher-value innovations.
  • Chinese Market Globalization: China is actively expanding globally, evidenced by a surge in high-value cross-border license-out deals.
  • Technology-Driven Efficiency: Advanced discovery engines—exemplified by Cyagen's HUGO-Ab platform and AI algorithms—are streamlining candidate screening, optimizing molecular design, and localizing the upstream supply chain.
  • Oncology-Focused Innovation: R&D pipelines remain heavily concentrated on high-incidence malignancies like non-small cell lung cancer, utilizing complex modalities to combat clinical resistance.
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