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B6-hLPA (CKI) /Alb-cre
Product ID:
C001522
Background:
C57BL/6NCya
Documents:
Click here to download >
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Basic Information
Model Name
B6-hLPA (CKI) /Alb-cre
Product ID
C001522
Gene Name
LPA
Background
C57BL/6NCya
Gene Alias
LP; AK38; APOA
Classification
Metabolic Target Humanized Models,Metabolic Disease Models
NCBI ID
4018
Phenotype
--
Chromosome
6
More
Rare Disease Data Center >>
Document
Click here to download >>
Note
Note: When using this mouse strain in a publication, please cite “B6-hLPA (CKI) /Alb-cre mice (Catalog C001522) were purchased from Cyagen.”
Strain Description
This strain was generated by mating B6-hLPA (CKI) mice (catalog number: C001521) with Alb-Cre mice (liver-specific Cre-expressing mice), resulting in a mouse model with liver-specific overexpression of the human LPA gene. B6-hLPA (CKI) /Alb-cre mice can be used to study the relationship between the LPA gene and hyperlipidemia and related cardiovascular diseases.
Application Area
Area
Research on atherosclerosis, hyperlipidemia, thrombotic cardiovascular diseases, etc.
Area
Preclinical evaluation of human LPA-targeted drugs
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