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hF11
Product ID:
C001272
Background:
C57BL/6NCya
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Strain Description
This strain is a humanized model of F11 in which the CDS of human F11 (hF11) is expressed under the regulation of the mouse endogenous F11 gene promoter, and the expression of the mouse F11 gene is disrupted to reduce cross-reactivity. This model can be used for in vivo efficacy assessment and analysis of diseases associated with human F11, and homozygous hF11 mice are viable and fertile.
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Area
Research on Rosenthal syndrome
Area
Research on the intrinsic pathway of blood coagulation
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