稳转细胞株助力基因功能研究

众所周知，生命科学的研究有很大一部分集中于研究基因及其产物的功能。而研究某个基因的功能最常用的手段是在宿主细胞中过表达或者沉默该基因，筛选稳定细胞株。稳转细胞株是开展基因功能研究、靶点验证及药物筛选的重要工具。

赛业生物细胞生物学技术平台已积累上万例项目经验，平台成熟稳定，提供的细胞基因编辑服务、稳转细胞株构建服务、病毒包装载体构建服务及干细胞诱导分化服务已帮数千名科研人员解决了科研难题，产品与技术已直接应用于包括CNS(Cell,Nature,Science)三大期刊在内的2400余篇学术论文。

精选文献期刊	年份	文章
J Exp Med	2017	Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy
Nat Commun	2018	AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle
Nat Microbiol	2018	The extracellular domain of Staphylococcus aureus LtaS binds insulin and induces insulin resistance during infection
Nat Commun	2018	De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis
Nat Commun	2018	Transposon-modified antigen-specific T lymphocytes for sustained therapeutic protein delivery in vivo
Genome Biol	2018	Distinctive epigenomes characterize glioma stem cells and their response to differentiation cues
Nat Commun	2018	Structure of the mouse TRPC4 ion channel
Nat Med	2018	Biochemical autoregulatory gene therapy for focal epilepsy
Nat Neurosci	2018	Variation among intact tissue samples reveals the core transcriptional features of human CNS cell classes
Nat Commun	2018	Mettl3-mediated m6A RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis

近期我们推出稳转细胞株服务促销活动，价格低至1.52万，周期快至8周，承诺项目失败全额退款。如果您有细胞株模型构建方面的需求或任何技术问题，欢迎回复本邮件或拔打400-680-8038联系我们。