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Treatment and Male-Bias in Autistic Mice
Although humans and mice are separated by 100 million years of evolution, mouse and rat models have continually proven themselves as extremely powerful research tools. Many mouse and rat genetic models can even recapitul... Read More ›
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Metastasis triggered by macrophage cytoplasm
Macrophages are the first line of defense against infections, playing important roles in consuming pathogens and in regulating inflammation. In general, these functions help maintain a healthy organism, keeping infection... Read More ›
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Anorexic mice
During the past several years, there has been an increasing public awareness of mental illness and their societal and health consequences. Eating disorders represent one of the most damaging groups of mental illnesses. C... Read More ›
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'Trimming the fat' with CRISPR
Around 20 million years ago, for unknown reasons, wild pigs lost an important metabolic gene known as uncoupling protein 1 (UCP1). In most mammals this gene plays a major role in generating body heat for thermoregulation... Read More ›
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A mammalian half-day clock
Last month, the Nobel Foundation recognized Jeffrey Hall, Michael Rosbash, and Michael Young "for their discoveries of molecular mechanisms controlling the circadian rhythm". This 24-hour "clock" influences many physiolo... Read More ›
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Is ApoE the key to an Alzheimer's cure?
Alzheimer’s disease has gained a lot of attention in the past week or so due to new findings about Apolipoprotein E (ApoE) published in Nature1. ApoE genotype has long been known to be a major risk factor for Alzheimer d... Read More ›
