Since the early 2000s, large-scale knockout consortia have been established with the goal of generating a complete resource of reporter-tagged null mutations in C57BL/6 mouse ES cells. Herein, ...... Read More ›
As CRISPR-based innovations begin to move into clinical testing and the dispute over core patents continues worldwide, CRISPR-Cas9 gene editing has been under increased scrutiny in both commercial ...... Read More ›
Synaptic impairment is known to be a prerequisite to the cognitive deficiencies exhibited in Alzheimer's Disease (AD), so investigating the mechanisms which... Read More ›
Nppa (natriuretic peptide A) is a cardiac hormone that dynamically changes its spatiotemporal expression during heart development.... Read More ›
Genetically engineered animals remain essential for gaining proper understanding of human disease mechanisms and play an important role in a variety of research areas.... Read More ›
Knockdown of TRB3 improved the MPP+/MPTP-induced Parkinson's disease through the MAPK and AKT signaling pathwa...
NeuroScience Letter 5;709:134352 (2019)
Fate decision of satellite cell differentiation and self-renewal by miR-31-IL34 axis.
CELL DEATH AND DIFFERENTIATION DOI://./10.1038/41418-019-0390- (2019)
TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis.
Nature Communications 2795 (2019) (2019)
Novel MicroRNA-455-3p and its protective effects against abnormal APP processing and amyloid beta toxicity in ...
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE :0925-4439 (19)30199-1 (2019)
Effect of EH domain containing protein 2 on the biological behavior of clear cell renal cell carcinoma.
Hum Exp Toxicol :10.1177/0960327119842241 (2019)
Inhibition of HtrA2 alleviated dextran sulfate sodium (DSS)-induced colitis by preventing necroptosis of intes...
Cell Death Dis 24;10 (5):344 (2019)
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