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  • Tel: 800-921-8930 or +1 408-969-0306 (Int'l) (8am-6pm Pacific Time)

    Email: animal-service@cyagen.com (Animal Model Services)
    animal-bank@cyagen.com (Cyagen Catalog Models)
    cell-service@cyagen.com (Cell Products and Services)

  • Custom Models
    Custom Mouse Models

    ■ ES cell based gene targeting services

    ● TurboKnockout® Knockout & Conditional KO Mice ● TurboKnockout® Humanized and Knockin Mice ● ES cell mediated Knockout & Knockin Mice

    ■ CRISPR/Cas9-based services

    ● Knockout Mice ● Point Mutation Mice ● Large-fragment Knockin Mice (any locus) ● Large-fragment Knockin Mice (ROSA26)

    ■ Transgenic services

    ● Regular Transgenic Mice ● Transgenic Mouse Embryos ● PiggyBac Transgenic Mice ● PiggyBac Transgenic Mouse Embryos ● PiggyBac-on-BAC Transgenic Mice
    Custom Rat Models

    ■ CRISPR/Cas9-based services

    ● Knockout Rats ● Point Mutation Rats ● Large-fragment Knockin Rats (any locus) ● Large-fragment Knockin Rats (ROSA26)

    ■ Transgenic services

    ● Regular Transgenic Rats ● PiggyBac Transgenic Rats ● PiggyBac-on-BAC Transgenic Rats
    Animal Model Supporting Services
    ● Breeding Service ● Cryopreservation Service ● Histology Service ● Transcriptome Profiling by RNA-Seq ● BAC Modification (Recombineering)
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Live KO/cKO Mice, Shipped in 2 Weeks, only $1,299
Grant Application Support Letter
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Live KO/cKO Mice
Shipped in 2 Weeks, only $1,299
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cKO | cKI
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cKO | KO | KI | PM | Humanized
PiggyBac Transgenic
Rats | Mice | Mouse Embryos
Promotions
  • ACE2 Model Validation Report
    ACE2 Model Validation Report

    In the wake of the COVID-19 pandemic, research teams around the globe are racing to develop vaccines and therapeutic options for the disease. Accurate animal models are essential ... Read More ›

  • Cyagen Ambassador Awards
    Cyagen Ambassador Awards

    Over the past 15 years, Cyagen has helped more than 3,000 university and company partners decipher the complexities of the genome in the most economical and accurate way. ... Read More ›

  • Grant Application Support Letter
    Grant Application Support Letter

    To give your grant proposal a competitive edge, Cyagen's model generation experts can provide a letter of support that clearly outlines model generation strategies, budget, and timeline - ... Read More ›

  • Free Homozygous Breeding
    Free Homozygous Breeding

    Since the Cyagen Knockout Catalog Models repository was established, it has delivered ready-to-use heterozygous gene knockout (KO) mice to researchers worldwide in as fast as 3 months. In ... Read More ›

  • Humanized ACE2 Mice in As Soon As 1 Month, From $800
    Humanized ACE2 Mice in As Soon As 1 Month, From $800

    As part of our continued development of ACE2 mouse models for COVID-19/SARS-CoV-2 research, we are excited to announce that new homozygous hACE2 mouse models are nearly ready for ... Read More ›

  • Cyagen's Lucky Draw for Knockout Mouse Catalog Models
    Cyagen's Lucky Draw for Knockout Mouse Catalog Models

    Celebrate Black Friday all November long by entering Cyagen’s Catalog Lucky Draw for Knockout Catalog Models. Established in 2020, the Cyagen Knockout Catalog Models repository provides ready-to-use gene ... Read More ›

Technical Bulletins
  • Rare Disease Day 2021 – Achieving Equity
    Rare Disease Day 2021 – Achieving Equity

    With over 300 million people worldwide living with a rare disease, Rare Disease Day aims to raise awareness of what it means to be rare. On the last ... Read More ›

  • 【Gene of the Week】Metabolism & Cardiovascular Diseases - SIRT3
    【Gene of the Week】Metabolism & Cardiovascular Diseases - SIR...

    The SIRT3 gene plays an important role in the pathogenesis of metabolic, cardiovascular, and neurodegenerative diseases. In this article, we review the functionality of SIRT3 and explore its ... Read More ›

  • The PiggyBAC Transposon - Generating Transgenic Mice with Consistent Expression
    The PiggyBAC Transposon - Generating Transgenic Mice with Co...

    In most experiments, scientists will try to minimize the number of independent variables so as not to confuse the results of an experiment. Due to the varying level ... Read More ›

  • [Gene of the Week] The Next Generation Target for Immunotherapy - CD134 (TNFRSF4)
    [Gene of the Week] The Next Generation Target for Immunother...

    Immune checkpoint proteins (ICP) are a group of signaling molecules possessed by immune cells that can regulate and control the persistence of immune response. The immune checkpoint signaling ... Read More ›

  • Beyond Alzheimer’s Disease – Implications of APOE in Viral Pathology
    Beyond Alzheimer’s Disease – Implications of APOE in Viral P...

    The APOE gene - which encodes Apolipoprotein E – has been extensively studied due to its biological relevance to a range of neurological and cardiovascular diseases, including Alzheimer’s ... Read More ›

  • One-Minute Survey: Cyagen Knockout Catalog Models Improve our offerings and receive $2,000 credit!
    One-Minute Survey: Cyagen Knockout Catalog Models Improve ou...

    Given your interest in and/or purchase from the Cyagen Knockout Catalog Models repository, we would appreciate your participation in a one-minute survey. Your feedback will be used to ... Read More ›

Citations
  • Lineage Tracing of Cells Expressing the Ciliary Gene IFT140 During Bone Development

    Developmental Dynamics. DOI: 10.1002/dvdy.266 (2020)

  • Shrm4 contributes to autophagy inhibition and neuroprotection following ischemic stroke by mediating GABA B re...

    FASEB J. DOI: 10.1096/fj.202000458RR (2020)

  • Neuraminidase-1 promotes heart failure after ischemia/reperfusion injury by affecting cardiomyocytes and invad...

    Basic Res Cardiol. DOI: 10.1007/s00395-020-00821-z (2020)

  • Suppression of DDX39B sensitizes ovarian cancer cells to DNA-damaging chemotherapeutic agents via destabilizin...

    Oncogene DOI: 10.1038/s41388-020-01482-x (2020)

  • The piRNA CHAPIR regulates cardiac hypertrophy by controlling METTL3-dependent N 6-methyladenosine methylation...

    Nat Cell Biol. DOI: 10.1038/s41556-020-0576-y (2020)

  • T cell immunoglobulin and mucin domain protein 3 inhibits glycolysis in RAW 264.7 macrophages through Hexokina...

    Scand J Immunol. DOI: 10.1111/sji.12981 (2020)

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Cyagen
  • address
    2255 Martin Avenue, Suite E
    Santa Clara, CA 95050-2709, US
  • phone
    800-921-8930 (8-6pm PST) or +1 408-969-0306 (Int'l)
  • fax
    408-969-0336
  • email
    animal-service@cyagen.com (Animal Model Services)
    animal-bank@cyagen.com (Cyagen Catalog Models)
    cell-service@cyagen.com (Cell Products and Services)
Services
  • ■ Animal Model Genaration
    • · TurboKnockout® Service (Conditional KO & KI Mice)
    • · ES cell mediated Knockout & Knockin Mice
    • · Point Mutation Mice (CRISPR/Cas9)
    • · CRISPR/Cas9 Knockout Mice
    • · Transgenic Mice
    • · Point Mutation Rats (CRISPR/Cas9)
    • · CRISPR/Cas9 Knockout Rats
    • · Transgenic Rats
  • ■ Animal Model Supporting Services
  • ■ Molecular Biology
Products
  • · Stem Cells
  • · Fluorescent-Labeled Cells
  • · Primary Cells
  • · Stem Cell Culture Media
  • · Stem Cell Differentiation Media
  • · Cell Cryopreservation Media
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About Us
  • · Citation
  • · Promotions
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  • · Online Support
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