BALB/c-Ighj KO
Product Type
Age
Genotype
Sex
Quantity
Price:
Contact for Pricing
Basic Information
Model Name
BALB/c-Ighj KO
Product ID
C001345
Gene Name
--
Background
BALB/cAnCya
Gene Alias
--
Classification
Immunodeficient Mouse Models
NCBI ID
--
Phenotype
Chromosome
--
More
--
Document
Note: When using this mouse strain in a publication, please cite “BALB/c-Ighj KO mice (Catalog C001345) were purchased from Cyagen.”
Strain Description
This strain is an Ighj-deletion model, in the homozygous BALB/c-Ighj KO mice, the J-segment of the Ig heavy chain locus is completely deleted, resulting in the inability of the cell to produce a recombinant version of the complete heavy chain variable region. The B cells of BALB/c-Ighj KO mice have undergone dramatic changes in the developmental process and cell number, which can be used as an animal model of B cell immune deficiency. BALB/c-Ighj KO mice retain other immune cells except for B cells, so the presence of other immune cells can be detected in BALB/c-Ighj KO mice.
Application Area
Immunological, inflammatory, and autoimmune diseases
Validation Data