B6RG
Product Type
Age
Genotype
Sex
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Basic Information
Model Name
B6RG
Product ID
C001367
Background
C57BL/6JCya
Gene Alias
Rag-2; gc; p64; [g]c; CD132; gamma(c)
Classification
Immunodeficient Mouse Models
Phenotype
--
Chromosome
2
Document
Note: When using this mouse strain in a publication, please cite “B6RG mice (Catalog C001367) were purchased from Cyagen.”
Strain Description
The B6RG mouse is a double gene knockout model of Rag2 and IL2rg on the C57BL/6 background. Homozygous B6RG mice develop normally and are fertile but do not produce mature T cells, B cells, or NK cells. They can be used in studies related to immune system deficiencies, cancer, toxicology, and xenotransplantation.
Application Area
Studies related to immune system deficiencies, cancer, toxicology, and xenotransplantation
Validation Data