NKG-H2-Ab1 KO
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Strain Description
NKG-H2-Ab1 KO mice are generated by knocking out the H2-Ab1 gene on the background of NKG mice. Compared to NKG mice, NKG-H2-Ab1 KO mice can effectively reconstitute CD8+ T cells and exhibit improved survival after PBMC transplantation. They can be used for long-term studies on PBMC immune system reconstitution.
Application Area
Establishment of humanized immune system mouse model
Research on graft-versus-host disease (GvHD)
Research on the immune system, hematopoietic system, and blood disease
Cell line-derived xenograft (CDX) and drug screening and efficacy evaluation
Patient-derived xenograft (PDX) and drug screening and efficacy evaluation
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