The ADIPOQ gene-encoded adiponectin is a protein hormone produced exclusively by adipocytes (fat cells). It is transported through the bloodstream to muscle and liver cells. In this model, the P2A-iCre gene expression element is inserted into the mouse endogenous Adipoq gene at the stop codon. Its specific expression is regulated by the mouse Adipoq gene. When this strain is crossed with mice containing loxP sites, sequence recombination mediated by the Cre recombinase between loxP sites can occur in the white adipose tissue (WAT) and brown adipose tissue (BAT) of its offspring.