NKG-MHC I/II dKO
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Strain Description
NKG-MHC I/II dKO mice were obtained by crossing NKG B2m KO mice (catalog No. C001416) with NKG-H2-Ab1 KO mice (catalog No. C001498), which were effective in delaying the onset of graft-versus-host disease (GvHD). This model can be used for long-term studies of PBMC immune system reconstitution.
Application Area
Establishment of humanized immune system mouse model
Research on graft-versus-host disease (GvHD)
Research on the immune system, hematopoietic system, and blood disease
Cell line-derived xenograft (CDX) and drug screening and efficacy evaluation
Patient-derived xenograft (PDX) and drug screening and efficacy evaluation
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