NKG B2m KO
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
NKG B2m KO
Product ID
C001416
Background
NKG
Gene Alias
gc; p64; [g]c; CD132; gamma(c); Ly-m11; beta2m; beta2-m
Classification
Immunodeficient Mouse Models
Chromosome
X
Document
Note: When using this mouse strain in a publication, please cite “NKG B2m KO mice (Catalog C001416) were purchased from Cyagen.”
Strain Description
NKG B2m KO mice are constructed by knocking out the B2m gene on the background of NKG mice. Compared with NKG mice, NKG B2m KO mice have a significantly longer survival period after PBMC transplantation and can be used for long-term studies of PBMC immune system reconstitution.
Application Area
Establishment of humanized immune system mouse model
Research on graft-versus-host disease (GvHD)
Research on the immune system, hematopoietic system, and blood disease
Cell line-derived xenograft (CDX) and drug screening and efficacy evaluation
Patient-derived xenograft (PDX) and drug screening and efficacy evaluation
Validation Data