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B6-hIL6
Product ID:
C001605
Background:
C57BL/6NCya
Documents:
Click here to download >
Product Type
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Genotype
Sex
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Price:
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Basic Information
Model Name
B6-hIL6
Product ID
C001605
Gene Name
IL6
Background
C57BL/6NCya
Gene Alias
CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2
Classification
Cytokine Humanized Models,Full-Gene Humanized Models,Autoimmune Disease Models
NCBI ID
3569
Phenotype
MGI:96559
Chromosome
7
More
Rare Disease Data Center >>
Document
Click here to download >>
Note
Note: When using this mouse strain in a publication, please cite “B6-hIL6 mice (Catalog C001605) were purchased from Cyagen.”
Strain Description
The B6-hIL6 mouse is an Il6 gene humanized model, in which the endogenous Il6 gene sequence in mice is replaced in situ with the human IL6 gene sequence. This model can be used in researching autoimmune diseases, inflammation-related diseases, cancer, and infectious diseases. It is also useful for the development, screening, and evaluation of IL6-targeted drugs.
Application Area
Area
Research on autoimmune diseases, inflammation-related diseases, cancer, and infectious diseases
Area
Preclinical studies on the development, screening, and evaluation of IL6-targeted drugs
Validation Data
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