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B6-hTROP2 (hTACSTD2)
Product ID:
C001718
Background:
C57BL/6NCya
Documents:
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Strain Description
The B6-hTROP2 (hTACSTD2) mouse is a humanized model constructed by replacing the signal peptide and extracellular domain (aa.1~270) of the mouse Tacstd2 with the corresponding signal peptide and extracellular domain (aa.1~274) from the human TACSTD2 gene. The B6-hTROP2 (hTACSTD2) mice can be used for studies on pathogenesis of various cancers, as well as for TACSTD2-targeted drug development.
Application Area
Area
TACSTD2-targeted drug screening, development, and evaluation
Area
Research on the pathological mechanisms and therapeutic approaches of various cancers
Area
Research on the pathological mechanisms and therapeutic approaches of gelatinous drop-like corneal dystrophy
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