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B6-hOX40L (hTNFSF4)
Product ID:
C001719
Background:
C57BL/6NCya
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Strain Description
B6-hOX40L (hTNFSF4) mice are a humanized model constructed by using gene editing technology to replace the endogenous extracellular domain of the mouse Tnfsf4 gene with the extracellular domain of the human TNFSF4 gene. This model can be used for research on autoimmune diseases (such as systemic lupus erythematosus and rheumatoid arthritis), cancer immunology, and TNFSF4-targeted drug development.
Application Area
Area
Screening, development, and preclinical efficacy evaluation of TNFSF4-targeted drugs
Area
Research on the pathological mechanisms and treatment methods of autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA)
Area
Research on cancer immunology
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