B6-hIL33
Product Type
Age
Genotype
Sex
Quantity
Price:
Contact for Pricing
Basic Information
Model Name
B6-hIL33
Product ID
C001722
Gene Name
Background
C57BL/6NCya
Gene Alias
DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26
Classification
Immune Target Humanized Models,Cytokine Humanized Models,Full-Gene Humanized Models,Autoimmune Disease Models
NCBI ID
Phenotype
Chromosome
9
Document
Note: When using this mouse strain in a publication, please cite “B6-hIL33 mice (Catalog C001722) were purchased from Cyagen.”
Strain Description
The B6-hIL33 mouse is a humanized model constructed by replacing the sequence of the mouse Il33 gene in situ with the corresponding sequence from the human IL33 gene. The B6-hIL33 mice can be used for studies on asthma, atopic dermatitis, allergic rhinitis, inflammatory bowel disease, and other inflammatory disorders, as well as for IL33-targeted drug development.
Application Area
IL33-targeted drug screening, development, and evaluation
Research on the pathological mechanisms and therapeutic approaches of asthma, atopic dermatitis, allergic rhinitis, and inflammatory bowel disease
Research on other inflammatory disorders
Validation Data