Ltf-iCre
Product ID:
C001729
Background:
C57BL/6NCya
Documents:
Expressing Tissues/Cells:
Female reproductive system, especially the endometrium (uterine epithelium)
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
Ltf-iCre
Product ID
C001729
Gene Name
Background
C57BL/6NCya
Gene Alias
Lf; Csp82; Ms10r; MMS10R
Classification
Cre Driver Lines
NCBI ID
Phenotype
Chromosome
9
Document
Note: When using this mouse strain in a publication, please cite “Ltf-iCre mice (Catalog C001729) were purchased from Cyagen.”
Strain Description
The LTF gene (lactoferrin gene) encodes a multifunctional iron-binding glycoprotein that belongs to the transferrin family. It is mainly expressed in mucosal secretions (such as milk, tears, saliva), neutrophils, mammary gland, and the epithelial cells of the respiratory and gastrointestinal tract, and is particularly abundant in milk. This gene is often used as a marker for mammary epithelial cells and some immune cells. The Ltf-iCre mice are obtained by integrating the Kozak-iCre-P2A expression cassette upstream of the start codon of the endogenous Ltf gene in mice through gene editing technology. Under the drive of the regulatory elements of the mouse Ltf gene, the iCre recombinase (a codon-optimized Cre recombinase) is expressed.
Validation Data