Adgrl2-3xGGGGS-mCherry
Product ID:
C001743
Background:
C57BL/6JCya
Documents:
Expressing Tissues/Cells:
Various tissues, including the brain and heart, and Adgrl2-positive cells
Product Type
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Genotype
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Quantity
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Basic Information
Model Name
Adgrl2-3xGGGGS-mCherry
Product ID
C001743
Gene Name
Background
C57BL/6JCya
Gene Alias
Lec1; Gm619; Lphh1; Lphn2; CIRL-2; mKIAA0786
Classification
Reporter Mouse Lines
NCBI ID
Phenotype
Chromosome
3
Document
Note: When using this mouse strain in a publication, please cite “Adgrl2-3xGGGGS-mCherry mice (Catalog C001743) were purchased from Cyagen.”
Strain Description
Adgrl2-3xGGGGS-mCherry mice are constructed by replacing the partial exon 1 coding region of the mouse Adgrl2 gene with HA signal peptide - HA tag - Mouse Adgrl2 CDS (without signal peptide) - 3xGGGGS - mCherry - rBG pA cassette using gene editing technology. The Adgrl2-3xGGGGS-mCherry mouse carries a red fluorescent protein (mCherry) expression cassette, making it a precise research model that maintains protein function while offering fluorescence visualization. This model is valuable for several key areas of study. For instance, it can be used for the spatio-temporal dynamic analysis of the Adgrl2 gene expression profile. Researchers can also utilize it for investigating neuronal development and synapse formation mechanisms. Furthermore, it enables live-animal dynamic tracking and real-time imaging observation, providing invaluable insights. Lastly, this model is well-suited for systematic studies of protein interaction networks and downstream signaling pathways.
Validation Data