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B6-hFAP
Product ID:
C001783
Background:
C57BL/6NCya
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Strain Description
The B6-hFAP mouse is a humanized model constructed by replacing the sequence from ATG start codon to partial intron 2 of the mouse Fap gene with the Kozak Human FAP CDS-3'UTR of Mouse Fap-WPRE-BGH pA cassette. B6-hFAP mice can be used for research into the pathogenesis of various malignant tumors, as well as for the screening, development, and safety evaluation of FAP-targeted drugs.
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FAP-targeted drug screening, development, and evaluation
Area
Research on the pathological mechanisms and therapeutic approaches of malignant tumors
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