B6-hIL31
Product Type
Age
Genotype
Sex
Quantity
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Contact for Pricing
Basic Information
Model Name
B6-hIL31
Product ID
C001784
Gene Name
Background
C57BL/6NCya
Gene Alias
IL-31
Classification
Cytokine Humanized Models,Full-Gene Humanized Models
NCBI ID
Phenotype
Chromosome
12
Document
Note: When using this mouse strain in a publication, please cite “B6-hIL31 mice (Catalog C001784) were purchased from Cyagen.”
Strain Description
The B6-hIL31 mouse is a humanized model, constructed by replacing the coding sequences of the endogenous mouse Il31 gene with the coding sequences of the human IL31 gene. B6-hIL31 mice can be used for research into the pathogenesis of various inflammatory diseases and cancers. They are also useful for the screening, development, and safety evaluation of IL31-targeted drugs.
Application Area
IL31-targeted drug screening, development, and evaluation
Research on the pathological mechanisms and therapeutic approaches of various inflammatory diseases and cancers
Validation Data