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B6-hTGFB2
Product ID:
C001792
Background:
C57BL/6NCya
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Strain Description
The B6-hTGFB2 mouse is a humanized model, constructed by replacing the partial coding sequences of mouse Tgfb2 exon 1 with the Kozak-Human TGFB2 CDS-3’UTR of the Human TGFB2-WPRE-BGH pA cassette. B6-hTGFB2 mice can be used for research into the pathogenesis of cardiovascular diseases, fibrosis, cancers, and developmental disorders. They are also useful for the screening, development, and safety evaluation of TGFB2-targeted drugs.
Application Area
Area
TGFB2-targeted drug screening, development, and evaluation
Area
Research on the pathological mechanisms and therapeutic approaches of cardiovascular diseases, cancers, fibrosis, and developmental disorders
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