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SD-hSCN10A (Nav1.8)
Product ID:
CR006
Background:
SD
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Strain Description
SD-hSCN10A (Nav1.8) rats are a Scn10a humanized model created by inserting the human SCN10A gene's coding sequence (CDS) and 3'UTR into the rat Scn10a gene. This model can be used for mechanistic studies of acute pain and diabetic peripheral neuropathic pain and the development, screening, and evaluation of analgesic drugs in preclinical research.
Application Area
Area
Mechanisms of acute pain, diabetic peripheral neuropathic pain, and postoperative pain
Area
Preclinical studies on the development, screening, and evaluation of analgesics targeting the Nav1.8 channel
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