C57BL/6JCya-9330159F19Rikem1/Cya
Common Name:
9330159F19Rik-KO
Product ID:
S-KO-04848
Background:
C57BL/6JCya
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Strain Name
9330159F19Rik-KO
Strain ID
KOCMP-212448-9330159F19Rik-B6J-VA
Gene Name
Product ID
S-KO-04848
Gene Alias
--
Background
C57BL/6JCya
NCBI ID
Modification
Conventional knockout
Chromosome
10
Phenotype
Document
Application
--
Note: When using this mouse strain in a publication, please cite “C57BL/6JCya-9330159F19Rikem1/Cya mice (Catalog S-KO-04848) were purchased from Cyagen.”
Strain Description
Ensembl Number
ENSMUST00000092627
NCBI RefSeq
NM_001162537
Target Region
Exon 2~6
Size of Effective Region
~11.0 kb
Detailed Document
Overview of Gene Research
9330159F19Rik, with currently no widely-known common aliases, has been found to be involved in pathways related to lipid, amino acid metabolism, insulin resistance, and extracellular matrix (ECM)-related processes based on the analysis of differentially expressed mRNAs in adipose tissues [1]. It is a key gene in the ceRNA regulatory network, suggesting its importance in regulating gene expression at the post-transcriptional level in adipose-related biological functions.
In a study comparing the adipose tissues of the sham group and the duodenal-jejunal bypass (DJB) group, 9330159F19Rik was identified as one of the 31 hub differentially expressed mRNAs in the ceRNA regulatory network of DElncRNAs and DEcircRNAs. This implies that DJB may impact adipose tissue remodeling of ECM and energy metabolism through the ceRNA network where 9330159F19Rik is involved [1].
In conclusion, 9330159F19Rik is crucial in the ceRNA regulatory network associated with adipose tissue's ECM remodeling and energy metabolism. Research on 9330159F19Rik, especially through in-vivo studies like the comparison in the DJB-related model, helps understand the molecular mechanisms underlying adipose-related metabolic processes, which may potentially contribute to the study of obesity-related diseases and metabolic disorders [1].
References:
1. Zhao, Qingnan, Cheng, Jiaxin, Gao, Aimei, Zhu, Han, Liang, Yongjun. 2023. Duodenal-Jejunal bypass improves metabolism and re-models extra cellular matrix through modulating ceRNA network. In Genomics, 115, 110744. doi:10.1016/j.ygeno.2023.110744. https://pubmed.ncbi.nlm.nih.gov/37972907/
Quality Control Standard
Sperm Test
Pre-cryopreservation: Measurement of sperm concentration, determination of sperm viability.
Post-cryopreservation: A vial of cryopreserved sperms is selected for in-vitro fertilization from each batch.
Environmental Standards:SPF
Available Region:Global
Source:Cyagen