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Animal Models
C57BL/6JCya-Mob4em1/Cya
Mob4 is located on chromosome 1 of mice. Nuclease Technology will be used to design sgRNA; Mob4 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Mobpem1/Cya
Mobp is located on chromosome 9 of mice. Nuclease Technology was used to design sgRNA; Mobp knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Hrobem1/Cya
Hrob is located on chromosome 11 of mice. Nuclease Technology was used to design sgRNA; Hrob knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Apobem1/Cya
Apob is located on chromosome 12 of mice. Nuclease Technology was used to design sgRNA; Apob knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6NCya-Obi1em1/Cya
Obi1 is located on chromosome 14 of mice. Nuclease Technology was used to design sgRNA; Obi1 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Elobem1/Cya
Elob is located on chromosome 17 of mice. Nuclease Technology was used to design sgRNA; Elob knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Tob2em1/Cya
Tob2 is located on chromosome 15 of mice. Nuclease Technology will be used to design sgRNA; Tob2 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Tob1em1/Cya
Tob1 is located on chromosome 11 of mice. Nuclease Technology was used to design sgRNA; Tob1 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Mobpem1/Cya
Mobp is located on chromosome 9 of mice. Nuclease Technology was used to design sgRNA; Mobp knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Nob1em1/Cya
Nob1 is located on chromosome 8 of mice. Nuclease Technology will be used to design sgRNA; Nob1 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
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Global Antibody Drug Industry Development BlueBook (Frost & Sullivan)
Key Insights
The industry is undergoing a rapid transformation driven by next-generation modalities, globalized markets, and upstream technological innovations.
  • Market Structural Shift: Monoclonal antibodies drive steady growth, but ADCs and bispecifics are rapidly accelerating, reshaping the market with higher-value innovations.
  • Chinese Market Globalization: China is actively expanding globally, evidenced by a surge in high-value cross-border license-out deals.
  • Technology-Driven Efficiency: Advanced discovery engines—exemplified by Cyagen's HUGO-Ab platform and AI algorithms—are streamlining candidate screening, optimizing molecular design, and localizing the upstream supply chain.
  • Oncology-Focused Innovation: R&D pipelines remain heavily concentrated on high-incidence malignancies like non-small cell lung cancer, utilizing complex modalities to combat clinical resistance.
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