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Animal Models
C57BL/6JCya-Qkiem1/Cya
Qki is located on chromosome 17 of mice. Nuclease Technology was used to design sgRNA; Qki knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Qkiem1flox/Cya
Qki is located on chromosome 17 of mice. SgRNA and ssDNA were designed using Nuclease Technology; Qki conditional knockout mice were obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Ccnqem1/Cya
Ccnq is located on chromosome 11 of mice. Nuclease Technology was used to design sgRNA; Ccnq knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Gnaqem1/Cya
Gnaq is located on chromosome 19 of mice. Nuclease Technology was used to design sgRNA; Gnaq knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Polqem1/Cya
Polq is located on chromosome 16 of mice. Nuclease Technology will be used to design sgRNA; Polq knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Helqem1/Cya
Helq is located on chromosome 5 of mice. Nuclease Technology was used to design sgRNA; Helq knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Polqem1/Cya
Polq is located on chromosome 16 of mice. Nuclease Technology was used to design sgRNA; Polq knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Qkiem1/Cya
Qki is located on chromosome 17 of mice. Nuclease Technology was used to design sgRNA; Qki knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Cpqem1/Cya
Cpq is located on chromosome 15 of mice. Nuclease Technology will be used to design sgRNA; Cpq knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Colqem1/Cya
Colq is located on chromosome 14 of mice. Nuclease Technology will be used to design sgRNA; Colq knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
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Global Antibody Drug Industry Development BlueBook (Frost & Sullivan)
Key Insights
The industry is undergoing a rapid transformation driven by next-generation modalities, globalized markets, and upstream technological innovations.
  • Market Structural Shift: Monoclonal antibodies drive steady growth, but ADCs and bispecifics are rapidly accelerating, reshaping the market with higher-value innovations.
  • Chinese Market Globalization: China is actively expanding globally, evidenced by a surge in high-value cross-border license-out deals.
  • Technology-Driven Efficiency: Advanced discovery engines—exemplified by Cyagen's HUGO-Ab platform and AI algorithms—are streamlining candidate screening, optimizing molecular design, and localizing the upstream supply chain.
  • Oncology-Focused Innovation: R&D pipelines remain heavily concentrated on high-incidence malignancies like non-small cell lung cancer, utilizing complex modalities to combat clinical resistance.
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