Mouse Models for Metabolism & Rare Disease Research

Explore Our Models

Subscribe

Models

HUGO Series 🌟

HUGO-GT™ (Humanized Genomic Ortholog)

HUGO-Ab™ (Humanized Genomic Ortholog for Antibody)

MouseAtlas Model Library

Research Models

Cre Mouse Lines

Humanized Target Gene Models

Metabolic Disease Models

Ophthalmic Disease Models

Neurological Disease Models

Autoimmune Disease Models

Immunodeficient Mouse Models

Humanized Immune System Mouse Models

Oncology & Immuno-oncology Models

Covid-19 Mouse Models

Cell Line Models

Knockout Cell Line Product Catalog

Tumor Cell Line Product Catalog

iPSC Cell Line Product Catalog

AAV Standard Product Catalog

Services

Preclinical Efficacy

Alzheimer's Disease (AD)

Parkinson's Disease (PD)

Huntington's Disease (HD)

Age-Related Macular Degeneration (AMD)

PBMC Humanized Mouse Models

Human Immune System (HIS) Mouse Model

Metabolic & Cardiovascular Diseases

Autoimmune & Inflammatory

Genetically Engineered Animals

Transgenic Mice

Transgenic Rats

Model Generation Techniques

Turboknockout^ᵀᴹ Gene Targeting

Cre-ESCs Gene Editing

Targeted Gene Editing

Regular Transgenic

PiggyBac Transgenesis

Breeding & Supporting Services

Breeding Services

Cryopreservation & Recovery

Phenotyping Services

BAC Modification

Virus Packaging

Adeno-associated Virus (AAV) Packaging

Lentivirus Packaging

Adenovirus Packaging

Custom Cell Line Services

Induced Pluripotent Stem Cells (iPSCs)

Knockout Cell Lines

Knockin Cell Lines

Point Mutation Cell Lines

Overexpression Cell Lines

Modalities

AI-Powered AAV Discovery

Oligonucleotide Therapy

Cell Immunotherapy

Resources

Events & Webinars

Blogs & Insights

Reference Databases

Peer-Reviewed Citations

Rare Disease Data Center

Cell iGeneEditor™ System

OriCell Cell Culture

About Us

Corporate Overview

Facility Overview

Animal Health & Welfare

Blogs & Insights

Explore the latest in biotech and research, crafted to inspire your next breakthrough.

Metabolism & Obesity

HFD+CCl4-Induced Metabolic Dysfunction-Associated Steatohepatitis (MASH/NASH) Mice

Vision Stolen by Years - Age-related Macular Degeneration

Pathogenic Genes of Rare Disease - SMN1 in Spinal Muscular Atrophy Research

Top Reads

Metabolism & Obesity

HFD+CCl4-Induced Metabolic Dysfunction-Associated Steatohepatitis (MASH/NASH) Mice

Vision Stolen by Years - Age-related Macular Degeneration

Pathogenic Genes of Rare Disease - SMN1 in Spinal Muscular Atrophy Research

New Updates

STEAP2 in Prostate Cancer: AstraZeneca’s Multi-Modality Bet on a Next-Wave Target

Hemophilia Gene Therapy & Next-Gen Treatments: F8/F9 Humanized Mouse Models for Preclinical Validation

Breaking the COPD Bottleneck: IL-33/ST2/IL1RAP Breakthroughs and the Power of Humanized Models

Understanding Athymic Nude Mice: Foxn1 Genetics, Immunology and Oncology CDX Applications

Ready to Elevate Your Research?

Discover how Cyagen can support your research. Let’s start a conversation.

Filter By

All Topics

Animal Science and Quality

Autoimmunity & Inflammation

Cardiovascular Research

Cell & Gene Therapy

Genetic Disorders and Genomics

Immunology

Infectious Diseases & Vaccines

Metabolism & Obesity

Neuroscience

Oncology

Ophthalmology

Precision Medicine & Biomarkers

Rare Diseases

Regenerative Biology

Milestones & Highlights

Filter By

STEAP2 in Prostate Cancer: AstraZeneca’s Multi-Modality Bet on a Next-Wave Target

Hemophilia Gene Therapy & Next-Gen Treatments: F8/F9 Humanized Mouse Models for Preclinical Validation

Breaking the COPD Bottleneck: IL-33/ST2/IL1RAP Breakthroughs and the Power of Humanized Models

Understanding Athymic Nude Mice: Foxn1 Genetics, Immunology and Oncology CDX Applications

Cell & Gene Therapy

Targeted AAV Delivery Strategies for Adipose Tissue: From the Discovery of the Novel BAT Target to In Vivo Validation

Lessons from the Lilly-AC Immune Expansion: Is the "Extracellular Tau Antibody" Era Over?

Targeting SNCA/TFRC and Overcoming the BBB: The Future of Parkinson’s Disease Therapeutics

Precision Medicine & Biomarkers

Overcoming the Species Barrier in cGAS-STING Drug Discovery: Why Humanized Mice are Essential for Translation

Cell & Gene Therapy

Breakthrough Glaucoma Research: Leveraging ANGPTL7 Humanized Models for Gene Therapy

1

2

3

4

5

6

...

18

19

More

Address:

2255 Martin Avenue, Suite E Santa Clara, CA 95050-2709, US

Tel:

800-921-8930 (8-6pm PST)

+1408-963-0306 (lnt’l)

Fax:

408-969-0336

Email:

inquiry@cyagen.com

Models

HUGO-Ab™ (Humanized Genomic Ortholog for Antibody)HUGO-GT™ (Humanized Genomic Ortholog)MouseAtlas Model Library Research Models

Services

Neuroscience Ophthalmology Oncology Metabolic & Cardiovascular Diseases Autoimmune & Inflammatory

About Us

Corporate Overview Facility Overview Animal Health & Welfare Health Reports Our Partners Careers Contact Us

Social Media

Disclaimer: Pricing and availability of our products and services vary by region. Listed prices are applicable to the specific countries. Please contact us for more information.

Copyright © 2025 Cyagen. All rights reserved.

Global Antibody Drug Industry Development BlueBook (Frost & Sullivan)

Key Insights

The industry is undergoing a rapid transformation driven by next-generation modalities, globalized markets, and upstream technological innovations.

Market Structural Shift: Monoclonal antibodies drive steady growth, but ADCs and bispecifics are rapidly accelerating, reshaping the market with higher-value innovations.
Chinese Market Globalization: China is actively expanding globally, evidenced by a surge in high-value cross-border license-out deals.
Technology-Driven Efficiency: Advanced discovery engines—exemplified by Cyagen's HUGO-Ab platform and AI algorithms—are streamlining candidate screening, optimizing molecular design, and localizing the upstream supply chain.
Oncology-Focused Innovation: R&D pipelines remain heavily concentrated on high-incidence malignancies like non-small cell lung cancer, utilizing complex modalities to combat clinical resistance.

Now Available for Download

Stay Updated with the Latest from Cyagen

Get the latest news on our research models, CRO services, scientific resources, and special offers—tailored to your research needs and delivered straight to your inbox.

Full Name

Email

Organization

Country

Areas of Interest

Main Area of Research