B6-hVEGFA
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Strain Description
The B6-hVEGFA mice were generated by replacing the mouse Vegfa gene sequence with the human VEGFA gene sequence, including the non-coding 3’ UTR region. This model expresses the human VEGFA protein. B6-hVEGFA mice can be used for mechanistic studies and efficacy evaluations of ophthalmic diseases such as Age-Related Macular Degeneration (AMD), Diabetic Retinopathy (DR), and corneal neovascularization, as well as for tumor development and cancer drug research.
Application Area
Research on Age-Related Macular Degeneration (AMD)
Research on Diabetic Retinopathy (DR)
Research on corneal neovascular diseases
Tumor development and cancer drug research
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