▶ Why Switch to Cyagen's NKG?

Engineered for human-relevant translational studies and extensively published in high-impact journals.
Produced in the US to Taconic's "OF" standard.

Severe Immunodeficiency

T/B/NK-null, allowing for maximum engraftment efficiency and reducing experimental variability.

Proven Engraftment Host

A highly consistent, validated platform to secure your high-value studies (PDX, PBMC, CD34+ HSC).

Reliable Local Production

Produced in the US to Taconic's "OF" standard. Avoid the high cost and effort of obtaining the models, in-house breeding, and maintenance—secure study-ready cohorts and free up valuable cage space.

Versatile Research Use

One platform for oncology, cell therapy, GvHD, and toxicology. Consolidate your studies to save vital research budget.

▶ Explore Our "OK to Switch" Program

We are inviting researchers to experience the benefits of our NKG mice breed in the US. This "OK to Switch" offer is designed to help you easily transition from your current models with zero risk and gap.

Application Period

November 5, 2025 - December 31, 2025 (Limited-time offer)

Eligibility

Researchers in the US or EU

Offer

Up to 15 free NKG mice per approved applicant

Add-on Service

Access to custom CD34 humanization services from Taconic (inquire for details)

Response Time

3–5 business days after submission

Apply for Free Trial

10 slots available. We encourage current NOG users to apply!

▶ Maximize Research Potential with More Enhanced Resources

Explore Complementary Tools for Your Research

Download Our NKG Mouse Brochure

Get detailed specifications, validation data (including PDX and PBMC data), and usage recommendations.

Watch Our Expert Webinar

Advancing Precision Oncology: Immune-Humanized Mice for Preclinical Drug Evaluation
April 24, 2025 | 9:00 AM PDT

Request Custom CD34 Humanization

Learn more about the add-on humanization service provided by Taconic to receive study-ready cohorts for your project.

▶ FAQ

Who qualifies for the free trial?

Researchers in the US or EU.

What is the "OF" standard?

"OF" stands for "Opportunist Free," a high-level health standard managed by Taconic, ensuring your models are free from specific pathogens that could interfere with your research.

We currently use NOG/NSG mice. Is the NKG model a comparable alternative?

Yes, it is a powerful alternative, validated for robust PDX, PBMC, and CD34 engraftment. This free trial is specifically designed to help you validate the "switch" for your research.

What about the CD34 humanization service?

This is an optional, paid service provided directly by our partner, Taconic. You can indicate your interest in the application form, and a specialist can discuss your project needs.

What happens after I submit the form?

We will review your application within 3–5 business days and get in touch.

▶ Begin Your Discovery Now

Ready to Switch? Apply Now for a Better, Quicker, Local-Made Alternative.

Don't let supply chain issues slow down your science. Apply for your free trial and see how US-produced NKG mice can provide a solid foundation for your translational research.

Apply for Free Trial

Up to 15 Mice

Applications open from November 5 to December 31, 2025!

▶ NKG Mice Free Trial

Cyagen is committed to protecting your privacy. The information collected will be used solely for evaluating your eligibility for the OK to Switch: NKG Mice Free Trial Campaign Program. Your data will not be shared with third parties without consent.

* Full Name

* Institution / Organization

* Job Role

* Work Email

Phone Number

* Country / Region

* Research Area

What immunodeficient mice are you currently using?

Nude Mice

NOD scid

NSG

NOG

B-NDG

NCG

Other severe immunodeficient mice

Estimated timeline for your study

Additional Notes or Questions

We will review your application and contact you within 3–5 business days.