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Il12rb1 KO
Product ID:
C001214
Background:
C57BL/6NCya
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Strain Description
Il12rb1 knockout (KO) homozygous mice exhibit reduced serum levels of interferon-gamma (IFN-γ) in response to recombinant IL-12 or lipopolysaccharide (LPS) treatment. Additionally, splenocytes from these mice activated by concanavalin A (ConA) in response to IL-12 cannot proliferate or secrete IFN-γ. These homozygous mice are viable and fertile.
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Immune System-Related Research
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